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Salmonella is a major foodborne pathogen of both animals and humans. This bacterium is responsible for considerable morbidity and mortality world-wide. Gastrointestinal infections with Salmonella are usually self-limiting and rarely require medical intervention. Bloodstream infections, on the other hand, are often fatal even with hospitalization. The presentation is focused on data about the transmission of Salmonella, the associated symptoms and also on the prevention procedures to be considered for a healthy lifestyle.